Bacteria-specific biomarkers in mouse-models of infections investigated by NMR spectroscopy
نویسندگان
چکیده
spectral data from E. coli, S. aureus and P. aeruginosa infected C57BL/6 wild-type mice, showing the separation between samples along the type of infection (Fig.1A) and scores plot of the metabolite concentrations found in TLR4 deficient mice with LPS treatment and E. coli infection (Fig.1B). Two components encapsulate 82 % (A) and 90 % (B) of the interclass variation. Fig.2: The coefficient plot shows the relative contribution that each metabolite makes to the difference between the classes of the PLS-plot in Fig.1B. Fig. 1A Fig. 2
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